How to get from Milan to Palermo
A real 5-leg route: train, bus. Door to door 20h 18m, from €169.
We compared the ways to travel from Milan to Palermo. The most useful door-to-door route takes 20h 18m by train, bus, 4 transfers. The two cities are about 888 km apart in a straight line. The price and operators below come from a real route search.
This fare comes from a search on September 1, 2026 and has not been refreshed since. Run a live search for today's price.
Milan to Palermo: cheapest or fastest?
All from the same recent search. Pick a tab: the legs, the timing and the difference from the others all change with it.
- 1Milan → Roma, di Roma Tiburtinatrain
Trenitalia·3h - 2Ciampino → Rome Anagninabus
FlixBus·15m - 3Rome Anagnina → RomebusCity transit·10m
- 4Rome → Rome TiburtinabusCity transit·10m
- 5Rome Tiburtina → PalermobusFlixBus·13h 55m
The best balance of price and time we found on this route.
How the trip from Milan to Palermo works
Start with a Trenitalia train from Milan to Roma, di Roma Tiburtina, about 3h. Transfer in Ciampino and continue by FlixBus bus on to Rome Anagnina (15 min). Transfer in Rome Anagnina and continue by City transit bus on to Rome (10 min). Transfer in Rome and continue by City transit bus on to Rome Tiburtina (10 min). Transfer in Rome Tiburtina and continue by FlixBus bus on to Palermo (13h 55m). In total it's roughly €169 over 20h 18m, 4 transfers.
Along the way to Palermo
DepartureMilan
Change hereRome AnagninaChange hereRomeWhat Omio sells on this route
Omio's own lowest fares, one per mode. These are starting prices for the route in general, not for a date you picked, and they are refreshed once a day.
Omio last refreshed these on Fri, Sep 4
Who runs Milan to Palermo
TrenitaliaMilan-Roma, di Roma TiburtinaBook →FlixBusCiampino-Rome Anagnina, Rome Tiburtina-PalermoBook →City transitRome Anagnina-Rome, Rome-Rome TiburtinaBook →On this route you travel with Trenitalia, FlixBus, City transit; Routavio does not add a booking fee.
Milan to Palermo: common questions
How long does it take to get from Milan to Palermo?+−
The most useful route takes about 20h 18m by train, bus, 4 transfers.
How far is Palermo from Milan?+−
About 888 km in a straight line. The real route on the ground or in the air is longer.
How much does Milan to Palermo cost?+−
The best price in our latest search was €169. The exact fare depends on your travel date.
Which operators run Milan to Palermo?+−
On this route you travel with Trenitalia, FlixBus, City transit.
What is the cheapest way to get from Milan to Palermo?+−
Usually a flexible date, or leaving from a nearby airport. A live search puts every option for your dates side by side.
Can I book directly?+−
Yes. Routavio sends you straight to the operator or an independent third-party provider. We never add a booking fee. The final fare and availability are confirmed by that provider.
Where to next
Other ways people search Milan to Palermo
- how to get from Milan to Palermo
- Milan to Palermo travel time
- Milan to Palermo distance
- cheapest way from Milan to Palermo