How to get from Madrid to Santander
A real 3-leg route: flight, bus. Door to door 24h 12m, from €104.
We compared the ways to travel from Madrid to Santander. The most useful door-to-door route takes 24h 12m by flight, bus, 2 transfers. The two cities are about 335 km apart in a straight line. The price and operators below come from a real route search.
This is the lowest fare we have recorded for this route in the last 14 days.
This fare comes from a search on September 1, 2026 and has not been refreshed since. Run a live search for today's price.
Madrid to Santander: cheapest or fastest?
All from the same recent search. Pick a tab: the legs, the timing and the difference from the others all change with it.
- 1Madrid–Barajas → Porto Airportflight
Ryanair·1h 20m - 2Porto → Bilbaobus
FlixBus·8h 40m - 3Bilbao Airport → SantanderbusRegional connection·2h 12m
The best balance of price and time we found on this route.
How the trip from Madrid to Santander works
Start with a Ryanair flight from Madrid to Porto, about 1h 20m. Transfer in Porto and continue by FlixBus bus on to Bilbao (8h 40m). Transfer in Bilbao and continue by Regional connection bus on to Santander (2h 12m). In total it's roughly €104 over 24h 12m, 2 transfers.
Along the way to Santander
DepartureMadrid
Change herePorto Airport
Change hereBilbaoWhat Omio sells on this route
Omio's own lowest fares, one per mode. These are starting prices for the route in general, not for a date you picked, and they are refreshed once a day.
Omio last refreshed these on Fri, Sep 4
Who runs Madrid to Santander
RyanairMadrid–Barajas-Porto AirportSee live options and dates →FlixBusPorto-BilbaoBook →Regional connectionBilbao Airport-SantanderBook →On this route you travel with Ryanair, FlixBus, Regional connection; Routavio does not add a booking fee.
Madrid to Santander: common questions
How long does it take to get from Madrid to Santander?+−
The most useful route takes about 24h 12m by flight, bus, 2 transfers.
How far is Santander from Madrid?+−
About 335 km in a straight line. The real route on the ground or in the air is longer.
How much does Madrid to Santander cost?+−
The best price in our latest search was €104. The exact fare depends on your travel date.
Are there direct flights from Madrid to Santander?+−
The most useful route we found connects: 2 transfers, 24h 12m in total. On flexible dates a live search sometimes turns up a nonstop.
How long is the flight from Madrid to Santander?+−
Counting the whole door-to-door trip we measured about 24h 12m. About 11h 15m of that is waiting between legs.
Which operators run Madrid to Santander?+−
On this route you travel with Ryanair, FlixBus, Regional connection.
What is the cheapest way to get from Madrid to Santander?+−
Usually a flexible date, or leaving from a nearby airport. A live search puts every option for your dates side by side.
Can I book directly?+−
Yes. Routavio sends you straight to the operator or an independent third-party provider. We never add a booking fee. The final fare and availability are confirmed by that provider.
Where to next
Other ways people search Madrid to Santander
- how to get from Madrid to Santander
- Madrid to Santander travel time
- Madrid to Santander distance
- cheapest way from Madrid to Santander
- Madrid to Santander flight time
- flights from Madrid to Santander
- Madrid Santander direct flights